A week ago I had the opportunity to give a presentation (slides/pdf) on the application of nonlinear mixed-effects models to degradation kinetics at SETAC Europe in Copenhagen. In case you find yourself wondering what these models are and why we are so enthusiastic about them, this presentation gives a …

I am very happy to be able to announce the publication of the article Taking Kinetic Evaluations of Degradation Data to the Next Level with Nonlinear Mixed-Effects Models. It originated from an investigation of model selection criteria commissioned by the German Federal Environment Agency. During the course of that work …

Mehr als 10 Jahre nach der Veröffentlichung der ersten Teile des R-Paketes 'mkin' freue ich mich nun, die Veröffentlichung von mkin Version 1.0 bekanntgeben zu können!

Die Versionsnummer soll darauf hindeuten dass das Paket erprobt und ausgereift ist. Signifikante Verbesserungen würden vermutlich einen neuen Ansatz erfordern.

Ich plane mkin …

Working on the application of nonlinear mixed-effects models to chemical degradation data, it became desirable to further speed up the solution of at least the most common degradation models used in the mkin package, simple first-order (SFO) decline of the parent compound coupled to SFO decline of a metabolite, or …